Barely Significant
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Mediation and moderation by inflammation and dietary patterns in heavy metal exposure effects on kidney function.

Sci Rep · 2025 · PMC12638307 · PMID 41272095

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a decreasing trendno p-value reported
The E-R relationship between log-transformed blood cadmium and eGFR was approximately U-shaped (decrease-increase), while the relationship between log-transformed blood lead and eGFR showed a decreasing trend.

also in 47,180 other papers

an increasing trendno p-value reported
The E-R relationships between log-transformed urine cadmium and lead with eGFR both showed decreasing trends, while the function between log-transformed urine mercury and eGFR showed an increasing trend.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.