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PTEN-deficient, chromosomal instability colorectal cancer is hypersensitive to STAT3 inhibition.

Int J Biol Sci · 2025 · PMC12640721 · PMID 41287778

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Similarly, we also found an increasing trend of defective spindle architecture and centrosomal integrity following over-activation of PLK1 signal in PTEN -/- CRC cells.

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