IFN-γ and IL-22 in premature ovarian insufficiency correlation with ovarian reserve markers and pathogenic implications: a cross-sectional study.

BMC Womens Health · 2025 · PMC12642147 · PMID 41286727

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highly significantno p-value reported

For IL-22, the AUC reached 0.735 (95% CI: 0.574–0.897) with a highly significant P-value of 0.009, demonstrating even stronger diagnostic differentiation capability compared to IFN-γ.

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