Multivariate genome-wide analysis reveals shared genetic architecture and brain structural correlates of human cognitive abilities.

Sci Rep · 2025 · PMC12644536 · PMID 41286184

Europe PMC DOI

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extremely significantP = 2.92 × 10 –8actually significant

Protein-coding regions displayed 11.29-fold enrichment, 5’ UTR regions achieved 8.00-fold enrichment, while extended intronic regions showed 1.32-fold enrichment at extremely significant levels ( P = 2.92 × 10 –8 ), suggesting that these regions may participate in complex genetic mechanisms through regulation of gene expression or function.

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