Brain endothelial HIF-1<i>α</i> exacerbates diabetes-associated cognitive impairment by accelerating glycolysis-driven lactate production.

Acta Pharm Sin B · 2025 · PMC12648004 · PMID 41311407

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a decreasing trendno p-value reported

Morphological analysis revealed a decreasing trend in both number and diameter of neurospheres in the AGEs-Lac group compared to the AGEs-NC group ( Fig. 5 G).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Brain endothelial HIF-1&lt;i&gt;α&lt;/i&gt; exacerbates diabetes-associated cognitive impairment by accelerating glycolysis-driven lactate production.

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Brain endothelial HIF-1<i>α</i> exacerbates diabetes-associated cognitive impairment by accelerating glycolysis-driven lactate production.