DNAzyme targeting RIP3 suppresses NLRP3-mediated necroinflammation for the treatment of inflammatory diseases.

Acta Pharm Sin B · 2025 · PMC12648105 · PMID 41311405

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a decreasing trendno p-value reported

Morever, the R3-Dz/S complex exhibited a decreasing trend in the distance between the dG 14 -N of catalytic loop and the rA 0 -H O2' of cleavage site region during the reaction ( Fig. 2 E).

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