Barely Significant
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Global, regional, national burden, trends and health inequality of neglected tropical diseases and malaria from 1990 to 2021.

BMC Infect Dis · 2025 · PMC12649024 · PMID 41291509

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an increasing trendno p-value reported
However, in High-income Asia Pacific, Australasia, and High-income North America, the ASIR showed an increasing trend from 1990 to 2021, with High-income Asia Pacific showing the largest increase.

also in 63,971 other papers

a decreasing trendno p-value reported
The prevalence, death rate, DALYs, and their corresponding ASR all showed a decreasing trend from 1990 to 2021.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.