Furthermore, functional prediction analysis of gut microbiota showed that the SCV-M group had the highest number of differential metabolic pathways, with the metabolic pathway PWY-7377, which is related to vitamin B12 synthesis, showing a highly significant difference compared to the control group ( Figure 6 f).
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Unlocking the Antioxidant Potential of Sea Cucumber Viscera: Pre-Treatment Modulates the Keap1-Nrf2 Pathway and Gut Microbiota to Attenuate Cold Stress-Induced Oxidative Damage.
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The average daily weight gain of mice in the CS group showed a decreasing trend, while the average daily food intake demonstrated an increasing trend compared to the control group ( Figure 2 c,d), these findings are consistent with the results of previous studies on chronic cold stress [ 43 ].