D-Dimer/Fibrinogen Ratio and Radiological Severity Scores in Acute Pulmonary Embolism: Is There Room for a New Thrombus-Burden Marker?

Diagnostics (Basel) · 2025 · PMC12651458 · PMID 41300899

Europe PMC DOI

hedged sentences

0.0280

closest p · 0.6× alpha

0.0545

boldest claim

The sentences

an increasing trendp = 0.028actually significant

Accordingly, the D-d/F showed an increasing trend in patients with HTB (median 0.63 vs. 0.88, p = 0.028) ( Figure 7 ).

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borderline significantp = 0.0545so close (0.05 < p ≤ 0.1)

Among the laboratory markers, the D-d/F ratio exhibited a significant positive weak correlation with IVC reflux (ρ = 0.247, 95% CI, 0.0649–0.414; p = 0.0085), while D-dimer showed a weaker, borderline significant correlation (ρ = 0.182, 95% CI, −0.00347–0.356; p = 0.0545).

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