Mechanisms of Intermittent Theta-Burst Stimulation Upregulates TFEB and Restores Autophagy to Play a Neuroprotective Role in the Acute Phase After Cerebral Ischemia Reperfusion.

Follow-up experiments revealed that rats in the MCAO group had a higher LC3-II/I ratio and increased SQSTM1 protein accumulation compared with the Sham group, while the expression levels of ATG5, ATG12, lysosomal markers CTSD and LAMP1 showed a decreasing trend (Fig. 7 A–G), suggesting that autophagic flow was blocked.

also in 47,180 other papers