Barely Significant
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Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy.

Sci Rep · 2025 · PMC12660706 · PMID 41309687

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a decreasing trendno p-value reported
A decreasing trend in melanin and erythema index was seen for each volunteer individually by TTA2G as compared to increase in the values with TTAsolG.

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highly significantno p-value reported
Hydration level The mean percentage change in moisture content of skin in volunteers was gradually increased in both cases of TTA2G and TTAsolG but results were found highly significant statistically for TTA2G which showed 68.5% moisture level after the 12th week while the level was found to be 27.6% by TTAsolG, as depicted in Fig. 5 c.

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