Within the hematoma, we identified a notable trend of CD8 + T cells transforming toward the CD8_GNLY subpopulation in patients with ICH, whereas the CD8 + T cells in controls were mainly retained in the naïve CD8_SELL state.
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FOXO1-driven metabolic reprogramming of hematomal CD8<sup>+</sup> T cells drives the expansion of perihematomal edema following intracerebral hemorrhage.
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