Suprachiasmatic Nuclei Possess Glucocorticoid Receptors That Activate Downstream Signaling Pathways but Do Not Entrain Their Circadian Clock.

Acta Physiol (Oxf) · 2026 · PMC12662659 · PMID 41314247

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highly significantp < 0.0001actually significant

We found a highly significant increase in the expression of Serum and glucocorticoid‐regulated kinase 1 ( Sgk1 , already 1 h after injection, two‐way ANOVA with Šidák's post hoc test, p < 0.0001) and Glucocorticoid‐induced leucine zipper protein ( Gilz / Tsc22d3 , 2 h after injection, p = 0.0015), both targets of GR transactivation.

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