Barely Significant
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Generating functional plasmid origins with OriGen.

Nucleic Acids Res · 2025 · PMC12663086 · PMID 41325770

Europe PMCDOI
1
hedged sentence
0.0010
closest p · 0.0× alpha
0.0010
boldest claim

The sentences

highly significantp < 0.001actually significant
None of these controls enabled replication, a result that was highly significant ( p < 0.001, one-sided Fisher’s exact test), suggesting that OriGen learned to preserve essential functional elements even in a replication system highly sensitive to mutations.

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