Additionally, the wet weights of tibialis anterior (TA) and extensor digitorum longus (EDL) muscles were higher in Pak4 KO mice compared with WT mice following dexamethasone treatment (Figure S4E,F ), while the soleus (SOL) muscle exhibited a nonsignificant trend toward increased weight (Figure S4G ).
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Negative Impact of p21-Activated Kinase 4-Mediated AMP-Activated Protein Kinase Inhibition on Sarcopenia in Mice and Humans.
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