Study and validation on mitochondrial and immune-related hub genes in gestational diabetes mellitus based on bioinformatics.

The expression levels of MRPL15, MRPL22, and MRPS18C all showed a decreasing trend during the differentiation of both monocytes and villous cytotrophoblast cells ( Figure 7I ). 3.8 Expression analysis results RT-qPCR results showed that MRPL15, MRPL22, and MRPS18C had significantly lower expression levels in the GDM group ( Figures 8A–C ). 4 Discussion With changes in social and economic life and dietary structure, the incidence of gestational obesity and its closely related GDM is increasing year by year ( 29 ).

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