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Botulinum toxin effects on biochemical biomarkers related to inflammation-associated head and neck chronic conditions: a systematic review of clinical research.

J Neural Transm (Vienna) · 2025 · PMC12669376 · PMID 40035830

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This exploratory pilot study also reported a decrease in baseline/interictal saliva CGRP levels for participants receiving BoNT, although this difference was only observed after the third month and narrowly missed statistical significance when compared to placebo-control group.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.