Sex-Specific Effects of Early-Life Unpredictability on Hippocampal and Amygdala Responses to Novelty in Adolescents.

Biol Psychiatry Glob Open Sci · 2025 · PMC12673399 · PMID 41346393

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closest p · 1.0× alpha

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failed to reach significancep < .05actually significant

For example, one study found that unpredictability was associated with frontolimbic structural connectivity among females but not males; however, the interaction failed to reach significance at the p < .05 threshold ( p = .086) ( 76 ).

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