During the course of treatment, there was a significant decrease in the level of IgM and only a decreasing trend in IgG levels ( Figure 5 ).
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Ocrelizumab transiently alters microbiota and modulates immune response depending on treatment outcome.
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The sentences
While an increasing trend towards to HCs was observed in responders at the end of month 12, non-responders continued to have low alpha diversity at this time point.