Telomere Length and Clear Cell Renal Cell Carcinoma: Unraveling Causal Mechanisms Through Integrative Genetic and Single-Cell Transcriptomic Analysis.

Mediators Inflamm · 2025 · PMC12677994 · PMID 41357133

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extraordinarily significantno p-value reported

The posterior probabilities for hypothesis H4 (shared causal variants) revealed extraordinarily significant colocalization signals: TL discovery set-ccRCC (PP.H4 = 98.3%) and TL validation set-ccRCC (PP.H4 = 99.7%), both substantially exceeding the robust colocalization threshold of 80%.

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