Fragmentation of nucleoli in senescent cancer cells is associated with increased levels of polyadenylated transcripts derived from noncoding regions of rDNA units.

Eur Biophys J · 2025 · PMC12678568 · PMID 40549171

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may be significantno p-value reported

It may be significant that out of the different rDNA subregions, the transcripts derived from 5’ ETS and ITS1 spacers exhibit largest dynamics following the transition from cycling to senescence.

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