Electroacupuncture Ameliorates Knee Osteoarthritis By Rebalancing T Cell Homeostasis as Revealed By Immune Repertoire (IR) Sequencing.

Compared to values prior to treatment in KOA patients, posttreatment values showed a highly significant rise in both the diversity index of TCRs and Shannon entropy ( P < 0.01) (Fig. 3C - E ). 3.2.3.

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Nonetheless, a decreasing trend was observed in the average scores of WOMAC pain, stiffness, function, and total scores as well as NRS scores (Supplementary Table 2 ). 3.2.

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The anti-inflammatory cytokines IL-10 and IL-13 were significantly higher posttreatment than pretreatment ( P < 0.01, both); there was no significant difference in IL-4, but it showed an increasing trend (Supplementary Fig. 4 ). 3.4.

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