Efficacy of DPMAS combined with PE in improving survival outcomes of patients with acute hepatitis E-induced liver failure: A retrospective cohort analysis.

Intragroup comparisons revealed significant improvement in the control group ( p = 0.024) and a highly significant improvement in the treatment group ( p < 0.001), indicating that the combined regimen achieved a more pronounced and clinically meaningful effect ( Table 2 ) 3.3 Survival analysis During the 6-month follow-up period, survival rates showed a gradual decline in both groups; however, the treatment group consistently demonstrated significantly higher survival rates than the control group at all predefined assessment time points (30, 90, and 180 days).

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Additionally, age ( p = 0.057), INR ( p = 0.080), infection ( p = 0.088), and hepatic encephalopathy ( p = 0.090) demonstrated trends toward marginal significance (0.05 < p < 0.10), likely reflecting the limited sample size and reduced statistical power.

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