Proteomics- and BRET- screens identify SPRY2 as a Ras effector that impacts its membrane organization.

iScience · 2025 · PMC12682140 · PMID 41362608

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highly significantno p-value reported

FLIM-FRET data supported a highly significant reduction in K-RasG12V membrane-FRET upon knockdown of either APLP2 or SPRY2 ( Figures 1 E, S3 E, and S3F).

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