a trend towards significancep < 0.1
Lactic acid showed a trend towards significance (p < 0.1, FDR-corrected).
Lactic acid showed a trend towards significance (p < 0.1, FDR-corrected).
Additionally, phospholipid levels showed an increasing trend in TBI patients ( Thomas et al., 2022 ).
In cases of TBI, significant alterations have been observed in the metabolism of branched-chain amino acids (BCAAs), with most related metabolites predominantly showing a decreasing trend; however, some studies have reported contradictory results ( Orešič et al., 2016 ; Jeter et al., 2013 ).