borderline significantp = 0.05
Subgroup Analyses Based on I2 and the p-value for heterogeneity, the progression of LGD to HGD or EAC showed borderline significant substantial heterogeneity (I2 = 66%; p = 0.05), LGD to HGD showed statistically insignificant low heterogeneity (I2 = 15%; p = 0.31), and LGD to EAC showed statistically insignificant moderate-to-substantial heterogeneity (I2 = 60%; p = 0.11).