In a murine model subjected to whole-body CS exposure for 4 weeks, lung glycolytic flux exhibited a decreasing trend, accompanied by enhanced activity of the PPP and downregulation of key glycolytic enzymes such as glyceraldehyde-3-phosphate dehydrogenase.
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Cigarette Smoking-Induced Glucose Metabolic Reprogramming in Chronic Obstructive Pulmonary Disease: Mechanisms and Therapeutic Implications.
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