Mixed-methods study assessing the acceptability and feasibility of Human Challenge Studies for Disease X in Healthy UK Adults in a SARS-CoV-2 pandemic setting.

BMJ Public Health · 2025 · PMC12684127 · PMID 41367542

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may be significantno p-value reported

1213 29 , 31 The precise role of CHIS in pandemic preparedness and pandemic responses is currently unclear but may be significant. 16 In the case of Disease X, where the pathogen, route of transmission, associated morbidity, mortality and long-term complications are unclear, the role and value of CHIS are understandably difficult to predict.

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