Nanoscale dynamics of enhancer-promoter interactions during exit from pluripotency.

Nucleic Acids Res · 2025 · PMC12684394 · PMID 41359380

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closest p

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highly significantno p-value reported

Notably, the largest, highly significant changes in E–P distance were observed between the Sox2 promoter and the Sox2 control region (SCR) (Δ n→p = 110 nm) as well as the Sox2 promoter and a putative enhancer ∼1280 kb downstream (Δ n→p = 110 nm) ( Supplementary Fig.

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