Proteomic Analysis of PTEN-Deficient Cells Reveals Src-Mediated Upregulation of EphA2 and Therapeutic Potential of Dual Inhibition.

Mol Cell Proteomics · 2025 · PMC12686823 · PMID 41130297

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highly significantno p-value reported

Cotreatment with dasatinib and capivasertib produced robust synergy in both models, with mean synergy scores of 11.73 in HCC1937 and 10.99 in SPAC-1-L cells, each with highly significant p values ( Fig. 8 , B – C ).

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