Dithiothreitol induced endoplasmic reticulum stress and its role in neurodegeneration in <i>Caenorhabditis elegans</i>.

Specifically, worms treated with 10 mmol/L DTT showed a highly significant decrease in bending frequency compared to the control group (0 mmol/L DTT) ( P < 0.01, n = 3), indicating impaired neuromuscular function under elevated ER stress (Figure 2C ).

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