Dexmedetomidine modulates gut microbiota and improves long-term survival in sepsis patients with pre-existing malignancies: a propensity-matched analysis.

Front Microbiol · 2025 · PMC12689500 · PMID 41383725

Europe PMC DOI

hedged sentence

0.1330

closest p · 2.7× alpha

0.1330

boldest claim

The sentences

approaching clinical significancep = 0.133not close (p > 0.1)

The sole variable approaching clinical significance was permanent drug discontinuation (11.9% vs. 17.5%; SMD 0.069; p = 0.133), though it remained below the prespecified imbalance threshold (SMD < 0.10).

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