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ALDH2 protects against dopaminergic neuronal cell ferroptosis by enhancing the enzyme activity of PRDX6 in Parkinson's disease.

NPJ Parkinsons Dis · 2025 · PMC12689773 · PMID 41330945

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an increasing trendno p-value reported
Lipid peroxides also increased after ALDH2 knockout, and there was an increasing trend of lipid peroxidation in the brains of rs671+MPTP mice compared to that in WT + MPTP mice, which was not significant.

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