Analysis of blood untargeted metabolomic characteristics of different subtypes of rosacea.

Front Mol Biosci · 2025 · PMC12695568 · PMID 41393510

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an elevated trendno p-value reported

4.2 Metabolites in PPR patients and their clinical significance 4.2.1 Anti-inflammatory fatty acids and compensatory repair mechanisms 12-hydroxystearic acid (12-HSA) showed an elevated trend in the blood of PPR patients. 12-HSA is a commonly used bioactive substance in skincare that can inhibit interleukin-1α (IL-1α) release and exert anti-inflammatory effects ( Mi et al., 2019 ).

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