Intra-Arterial Thrombolysis After Mechanical Thrombectomy in Patients with Acute Ischemic Stroke: A Systematic Review and Meta-Analysis With Trial Sequential Analysis.

31 However, it reported a significantly higher rate of any intracranial hemorrhage with IVT plus endovascular treatment (OR, 0.82 [95% CI, 0.68–0.99]), whereas our analysis showed a nonsignificant trend toward increased risk with IAT (OR, 1.30 [95% CI, 0.96–1.96]), indicating a potential safety concern that warrants further investigation.

also in 5,406 other papers