Barely Significant
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Association Between Chronic Kidney Disease and Glaucoma: Results From the Lifelines Cohort Study and UK Biobank.

Invest Ophthalmol Vis Sci · 2025 · PMC12697689 · PMID 41334958

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hedged sentence
0.0600
closest p · 1.2× alpha
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boldest claim

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borderline significantP = 0.06so close (0.05 < p ≤ 0.1)
However, we found a significant positive association of glaucoma PRS with eGFR in the UK Biobank (β = 0.15, 95% CI = 0.07 to 0.23, P = 0.0002), with similar effect size in Lifelines although it was only borderline significant (β = 0.20, 95% CI = –0.01 to 0.43, P = 0.06).

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