Cadherin 11 regulates presynaptic vesicle trafficking and neuronal activity in autism-related brain circuit.

Mol Psychiatry · 2026 · PMC12700811 · PMID 40796696

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Consistent with the findings from proteomic profiling, Western blotting confirmed a significant reduction in the membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (MAGI2) and an increasing trend of the vesicle transport through interaction with t-SNAREs homolog 1 A (VTI1A) in the ACC of EcKO mice (Fig. 6C and D ).

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