Formate Reduces Ischemic Injury in Female Hearts Lacking Alcohol Dehydrogenase 5.

FASEB Bioadv · 2025 · PMC12701282 · PMID 41393826

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a statistical trendno p-value reported

Interestingly, we found that MTHFD1/2 inhibition substantially increased infarct size in intact WT female hearts (Figure 5A,B ), but this increase was not statistically significant, as we only observed a statistical trend.

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