Barely Significant
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Comment on "The Effect of Epigenetic Age Acceleration on Atopic Dermatitis: A Mendelian Randomization Study" [Letter].

Clin Cosmet Investig Dermatol · 2025 · PMC12702275 · PMID 41399716

1
hedged sentence
0.0460
closest p · 0.9× alpha
0.0460
boldest claim

The sentences

borderline significancep = 0.046actually significant
4 , 5 This factor may contribute to the borderline significance (p = 0.046) observed for HannumAge acceleration, highlighting the need for explicit checks or adjustments in future studies to maintain the validity of causal inferences.

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