Safety and efficacy of AAV8-aflibercept in treating choroidal neovascularization via single-cell RNA sequencing.

Mol Ther Methods Clin Dev · 2025 · PMC12702363 · PMID 41399432

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a decreasing trendno p-value reported

Although mRNA levels increased at higher doses (2 × 10 9 GC/eye and 5 × 10 9 GC/eye) compared to the 1 × 10 9 GC/eye dose, protein expression levels did not correspondingly rise and even showed a decreasing trend.

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