Global, regional, and national burden of premenstrual syndrome from 1990 to 2021 and projections to 2050: an analysis based on the 2021 Global Burden of Disease study.

Front Psychiatry · 2025 · PMC12703365 · PMID 41403893

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an increasing trendno p-value reported

Conclusion Overall, the global burden of PMS has shown an increasing trend from 1990 to 2021.

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a decreasing trendno p-value reported

Similarly, projected global YLDs number for PMS also showed a decreasing trend ( Figure 8 ).

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practically significantno p-value reported

This suggests that closer collaboration between mental health services and medical systems at the societal level could be a practically significant step towards reducing the PMS burden and promoting global women’s mental health.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.