Association between intraoperative dexmedetomidine and survival outcomes after colorectal cancer surgery: a retrospective cohort study.

Front Oncol · 2025 · PMC12705362 · PMID 41409241

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an increasing trendno p-value reported

In a follow-up analysis of patients with laparoscopic resection of colorectal cancer, DEX did not improve overall survival and disease-free survival but presented an increasing trend in overall survival and disease-free survival, indicating that the use of DEX may benefit the long-term prognosis of patients undergoing laparoscopic resection of colorectal cancer ( 19 ).

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marginal significanceno p-value reported

The risk of recurrence or death was lower with a marginal significance (HR and 95% CI: 0.75, 0.56–1.01) in matched patients.

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