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Clinical features of hearing loss and genotype-phenotype correlations in Alport syndrome caused by COL4A4 or COL4A5 variants.

Sci Rep · 2025 · PMC12705733 · PMID 41398421

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a possible trendno p-value reported
4 , our findings suggest a possible trend toward a relationship between hearing phenotypes and genotypes, in terms of both hearing levels and hearing loss onset; genetic variants with high impacts on the protein were associated with more severe hearing loss and earlier age of hearing loss onset.

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