Proteomic Characterization Reveals CYP2S1 as a Mediator of Drug Resistance in PDAC.

Pancreas · 2026 · PMC12713692 · PMID 41001906

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highly significantno p-value reported

Consistent with the working hypothesis, both PACO18 and PACO10 cells showed a strong and highly significant decrease in cell survival upon SN38 treatment, if either AHR or CYP2S1 was subjected to knockdown (Fig. 6 A).

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