The role of interleukin-37 and interleukin-38 in the development and remission of autism spectrum disorder: a comprehensive review of neuroinflammatory mechanisms and potential therapeutic implications.

Front Immunol · 2025 · PMC12715017 · PMID 41425587

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may be significantno p-value reported

4.5 Maternal immune activation and developmental programming Maternal immunological activation, is a recognized risk factor for autism, presents an additional scenario in which IL-38’s protective effects may be significant ( 51 , 52 ).

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