Association between introduction of 13-valent pneumococcal conjugate vaccine and burden of hospitalized adult pneumococcal disease in Hong Kong - A retrospective database study.

13 , 14 However, this protection may not be significant as only a minor herd effect was observed in some European countries. 15 , 16 Possible reasons for the varying effectiveness of PCV across territories could be due to geographical differences in the prevalence of circulating pneumococcal serotypes and vaccine coverage rates. 17 In Hong Kong, there is limited information on the burden of pneumococcal disease and the effectiveness of vaccination.

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