Chronic stress promotes pancreatic ductal adenocarcinoma progression via complement C5a-recruited myeloid-derived suppressor cells.

Cancer Immunol Immunother · 2025 · PMC12717323 · PMID 41417111

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a decreasing trendno p-value reported

In the OFT, the total distance traveled showed a decreasing trend but did not differ significantly between PDAC and CUMS/PDAC mice, indicating that chronic stress did not markedly impair basal locomotor activity (Fig. 1 B and C ).

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