Cross-sectional mediation analysis of systemic inflammation in the association between serum uric acid and diabetic kidney disease: Evidence from NHANES 1999-2018.

Metabol Open · 2025 · PMC12721052 · PMID 41438208

Europe PMC DOI

hedged sentence

0.0690

closest p · 1.4× alpha

0.0690

boldest claim

The sentences

borderline significantp = 0.069so close (0.05 < p ≤ 0.1)

In an exploratory subgroup analysis restricted to participants with hyperuricemia, the mediated proportion increased to 39.68 %; however, the total effect in this subgroup was only borderline significant (p = 0.069), limiting interpretability.

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