The effectiveness of educational, behavioural, and cognitive self-management support interventions for chronic migraine: a systematic review.

Prim Health Care Res Dev · 2025 · PMC12721982 · PMID 41332176

Europe PMC DOI

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failed to reach significanceno p-value reported

( 2016 ) failed to reach significance as their participants had comorbid insomnia, and simple behavioural sleep instructions may not be sufficient to achieve a clinically meaningful change in this population.

also in 4,113 other papers

borderline significanceno p-value reported

(2016 ) reported borderline significance between groups for the reduction in depression scores at six weeks.

also in 7,017 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.