Shaoyao Gancao decoction alleviates functional constipation by inhibiting <i>Escherichia-Shigella</i> expansion, modulating gut microbiota, and suppressing dysbiosis-induced endocannabinoid production: evidence from a self-controlled pilot study.

Front Cell Infect Microbiol · 2025 · PMC12722481 · PMID 41446282

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a decreasing trendno p-value reported

SCFA profile changes SGD significantly increased total SCFA levels, especially acetate, propionate, and butyrate, while branched-chain SCFAs (isobutyrate, valerate, and isovalerate) showed a decreasing trend ( Figure 4 ).

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Shaoyao Gancao decoction alleviates functional constipation by inhibiting &lt;i&gt;Escherichia-Shigella&lt;/i&gt; expansion, modulating gut microbiota, and suppressing dysbiosis-induced endocannabinoid production: evidence from a self-controlled pilot study.

The sentences

Shaoyao Gancao decoction alleviates functional constipation by inhibiting <i>Escherichia-Shigella</i> expansion, modulating gut microbiota, and suppressing dysbiosis-induced endocannabinoid production: evidence from a self-controlled pilot study.